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This post has been migrated, original date 17 Dec 2008 Just blogging this because I am sure that I will have the problem later and want to know how to solve it. After changing some code on my website and recompiling it I got the following error: Loading this assembly would produce a different grant set from other instances After a few muttered four letter words I asked around the team and Stephen gave me the answer. The solution:
  1. Stop IIS
  2. Delete files in C:\WINDOWS\Microsoft.NET\Framework\v2.0.50727\Temporary ASP.NET Files